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LUDC-IRC ready for take off

Taking advantage of a novel sub-classification of diabetes LUDC-IRC, a newly launched collaboration between academia, the health care system and industry, aims at delivering precision medicine in diabetes.  - We have set the bar high. We very specifically aim at making a difference for diabetes patients by the end of this eight year program. We need to find smart ways to use all resources we colle

https://www.ludc.lu.se/article/ludc-irc-ready-take - 2025-10-03

Newborn babies to be screened for studies on type 1 diabetes and celiac disease (gluten intolerance)

Can insulin taken as an infant in small doses together with food render the immune system used to insulin and thus prevent type 1 diabetes? Can a gluten-free diet and probiotics prevent celiac disease (so called gluten intolerance)? These questions will be asked by two separate studies that are being planned at Lund University in Sweden. A new comprehensive screening of newborn babies in southern

https://www.ludc.lu.se/article/newborn-babies-be-screened-studies-type-1-diabetes-and-celiac-disease-gluten-intolerance - 2025-10-03

New drink keeps blood sugar in check

Food researchers at Lund University in Sweden have discovered that consuming small amounts of chromium mixed with certain amino acids before eating is healthy. Why? Well, this mixture diluted in water suppresses the blood sugar spike that occurs when we eat. Now, they are hoping that the drink – which tastes like ordinary mineral water – will be able to compete with soft drinks and flavoured water

https://www.ludc.lu.se/article/new-drink-keeps-blood-sugar-check - 2025-10-03

The risk of type 1 diabetes not increased by swine flu vaccine Pandemrix

There has been a fear that the swine flu vaccine, Pandemrix, would increase the risk of autoimmune diseases other than narcolepsy. However, a new study of children from Sweden and Finland shows that the vaccine increased neither the risk of developing autoantibodies against insulin-producing beta cells nor the occurrence of type 1 diabetes. “On the contrary, the risk was reduced among vaccinated c

https://www.ludc.lu.se/article/risk-type-1-diabetes-not-increased-swine-flu-vaccine-pandemrix - 2025-10-03

“Death receptors” – new markers for type 2 diabetes and cardiovascular disease

Researchers at Lund University in Sweden have found that the presence of death receptors in the blood can be used to directly measure the risk of developing cardiovascular diseases and type 2 diabetes. “We see that people with known risk factors such as high blood sugar and high blood fats also have heightened death receptor levels”, says Professor Jan Nilsson who led the study. Death receptors ar

https://www.ludc.lu.se/article/death-receptors-new-markers-type-2-diabetes-and-cardiovascular-disease - 2025-10-03

Nordic conference in Malmö about Precision Medicine in the future

December 4-5, nordic researchers gathered in Malmö to discuss future challenges in precision medicine, a research field where diagnosis and treatment are based on the individual´s genetic and biological conditions. Focus is on our common and increasing diseases diabetes, cardiovascular disease, cancer and psychiatric diagnosis. "The goal of the meeting is to bring together mordic stakeholders in p

https://www.ludc.lu.se/article/nordic-conference-malmo-about-precision-medicine-future - 2025-10-03

Paradigm shift in the diagnosis of diabetes

A completely new classification of diabetes which also predicts the risk of serious complications and provides treatment suggestions. We are now seeing the first results of ANDIS – a study covering all newly diagnosed diabetics in southern Sweden — published in The Lancet Diabetes & Endocrinology. The major difference from today’s classification is that type 2 diabetes actually consists of several

https://www.ludc.lu.se/article/paradigm-shift-diagnosis-diabetes - 2025-10-03

Opposites Attract: Assortative Mating and Immigrant–Native Intermarriage in Contemporary Sweden

This paper studies how immigrant–native intermarriages in Sweden are associated with individual characteristics of native men and women and patterns of assortative mating. Patterns of educational- and age-assortative mating that are similar to those found in native–native marriages may reflect openness to immigrant groups, whereas assortative mating patterns that indicate status considerations sug

https://www.lupop.lu.se/article/opposites-attract-assortative-mating-and-immigrant-native-intermarriage-contemporary-sweden - 2025-10-03

Psoriasis is Associated with a High Comedication Burden: A Population Based Register Study

A large body of evidence supports the association between psoriasis and concomitant diseases. However, the study of comedication for these diseases in patients with psoriasis is limited. The current study aimed to investigate the prescription and drug dispensation for comorbidity associated with psoriasis. Read more at https://link.springer.com/article/10.1007/s13555-020-00442-3

https://www.lupop.lu.se/article/psoriasis-associated-high-comedication-burden-population-based-register-study - 2025-10-03

The association between sociodemographic characteristics and dementia in patients with atrial fibrillation

We studied AF patients ≥ 45 years in Sweden 1998-2012 (n = 537,513) using the Total Population Register for socio-demographic factors, the Swedish Cause of Death Register, and the National Patient Register (NPR) for incident dementia. Cox regression with hazard ratios (HR) and 95% confidence intervals (CI) was used for the association between exposure and outcome, adjusting for age and comorbiditi

https://www.lupop.lu.se/article/association-between-sociodemographic-characteristics-and-dementia-patients-atrial-fibrillation - 2025-10-03

Mammographic density changes during neoadjuvant breast cancer treatment: NeoDense, a prospective study in Sweden

We prospectively included 200 breast cancer patients assigned to neoadjuvant chemotherapy (NACT) in the NeoDense study (2014–2019). Raw data mammograms were used to assess MD with a fully automated volumetric method and radiologists categorized MD using the Breast Imaging-Reporting and Data System (BI-RADS), 5th Edition. Logistic regression was used to calculate odds ratios (OR) for pCR comparing

https://www.lupop.lu.se/article/mammographic-density-changes-during-neoadjuvant-breast-cancer-treatment-neodense-prospective-study - 2025-10-03

Risk of Recurrent Disease 6 Years After Open or Robotic-assisted Radical Prostatectomy in the Prospective Controlled Trial LAPPRO

Conclusive evidence of superiority in oncological outcome for robot-assisted laparoscopic prostatectomy (RALP) over retropubic radical prostatectomy (RRP) is lacking. Read more at https://www.sciencedirect.com/science/article/pii/S2666168320351235

https://www.lupop.lu.se/article/risk-recurrent-disease-6-years-after-open-or-robotic-assisted-radical-prostatectomy-prospective - 2025-10-03

Neighborhood socioeconomic status and aortic stenosis: A Swedish study based on nationwide registries and an echocardiographic screening cohort

Aortic stenosis (AS) is the most common valvular heart disease in developed countries, confers high mortality in advanced cases, but can effectively be reversed using endovascular or open-heart surgery. We evaluated the association between AS and neighborhood socioeconomic status (NSES). Read more at https://www.sciencedirect.com/science/article/pii/S0167527320334124

https://www.lupop.lu.se/article/neighborhood-socioeconomic-status-and-aortic-stenosis-swedish-study-based-nationwide-registries-and - 2025-10-03

Polymorphism in killer cell immunoglobulin-like receptors and human leukocyte antigen-c and predisposition to preeclampsia in Ethiopian pregnant women population

Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2–8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate the association

https://www.lupop.lu.se/article/polymorphism-killer-cell-immunoglobulin-receptors-and-human-leukocyte-antigen-c-and-predisposition - 2025-10-03

Social class and fertility: A long-run analysis of Southern Sweden, 1922–2015

This paper examines social class differences in fertility, using longitudinal micro-level data for a regional sample in Sweden, 1922–2015. Using discrete-time event history models, we estimated the association between social class and parity-specific duration to next birth, adjusting for household income in separate models. Social class was associated with fertility quite independently from income

https://www.lupop.lu.se/article/social-class-and-fertility-long-run-analysis-southern-sweden-1922-2015-0 - 2025-10-03

Perceived job strain among Swedish occupational therapists with less than 10 years of work experience

In this cross-sectional study, a web-based survey was sent to 345 occupational therapists with less than 10 years of work experience, with 252 responding. Data was collected using the Swedish Demand-Control-Support Questionnaire and questions on job strain and sociodemographics. Read more at https://www.tandfonline.com/doi/full/10.1080/11038128.2020.1817544

https://www.lupop.lu.se/article/perceived-job-strain-among-swedish-occupational-therapists-less-10-years-work-experience - 2025-10-03

Patient-reported outcomes of joint-preserving surgery for moderate hallux rigidus: a 1-year follow-up of 296 patients from Swefoot

Hallux rigidus (HR), which affects approximately 2% of the population, can be graded based on the severity of the disease (Lucas et al. 2015, Lam et al. 2017, Galois et al. 2020). Beeson et al. (2008) conducted a literature review of the existing multiple classification systems where the system promoted by Coughlin and Shurnas (2003) was deemed to have the most reliable grading. Read more at https

https://www.lupop.lu.se/article/patient-reported-outcomes-joint-preserving-surgery-moderate-hallux-rigidus-1-year-follow-296 - 2025-10-03

Improvements in esophageal and gastric cancer care in Sweden-population-based results 2007–2016 from a national quality register

The Swedish National Register for Esophageal and Gastric cancer was launched in 2006 and contains data with adequate national coverage and of high internal validity on patients diagnosed with these tumors. The aim of this study was to describe the evolution of esophageal and gastric cancer care as reflected in a population-based clinical registry. The study population was 12,242 patients (6,926 wi

https://www.lupop.lu.se/article/improvements-esophageal-and-gastric-cancer-care-sweden-population-based-results-2007-2016-national - 2025-10-03

Higher Risk of Loosening for a Four-Pegged TKA Tibial Baseplate Than for a Stemmed One: A Register-based Study.

Modern modular implants allow surgeons to mix different combinations of components within the same brand. From 1999 to 2012, the NexGen®-CR Option femoral component, together with a NexGen® Option Stemmed tibial plate (stemmed baseplate), which uses a short central stem, was the most-frequently used NexGen® combination in the Swedish Knee Arthroplasty Register. However, from 1999 to 2012, the same

https://www.lupop.lu.se/article/higher-risk-loosening-four-pegged-tka-tibial-baseplate-stemmed-one-register-based-study - 2025-10-03